Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
Abstract Published November 2017 Pancreatic ductal adenocarcinoma is a lethal cancer with fewer than 7% of patients surviving past 5 years. T-cell immunity has been linked to the exceptional outcome of the few long-term survivors, yet the relevant antigens remain unknown. Here we use genetic, immunohistochemical and transcriptional immunoprofiling, computational biophysics, and functional assays to … Continue reading Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
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