1.0Sydney Gastroenterologyhttps://sydneygi.com.auinfo@sydneygi.com.auhttps://sydneygi.com.au/author/infosydneygi-com-au/The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. - Sydney Gastroenterologyrich600338<blockquote class="wp-embedded-content"><a href="https://sydneygi.com.au/deubiquitinase-usp9x-suppresses-pancreatic-ductal-adenocarcinoma/">The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.</a></blockquote>
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</script><iframe sandbox="allow-scripts" security="restricted" src="https://sydneygi.com.au/deubiquitinase-usp9x-suppresses-pancreatic-ductal-adenocarcinoma/embed/" width="600" height="338" title="“The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.” — Sydney Gastroenterology" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe>Abstract Pancreatic ductal adenocarcinoma (PDA) remains a lethal malignancy despite much progress concerning its molecular characterization. PDA tumours harbour four signature somatic mutations in addition to numerous lower frequency genetic events of uncertain significance. Here we use Sleeping Beauty (SB) transposon-mediated insertional mutagenesis in a mouse model of pancreatic ductal preneoplasia to identify genes that […]